Combine beef, 1 cup of cherries, onion, salt, pepper, pumpkin pie spice, garlic powder, and eggs in a large bowl. Mix them all together until well incorporated.
Once well incorporated, place the meat mixture on baking paper and flatten it into a rectangle at about one half inch thickness. The short side of your rectangle should be no longer than your loaf pan.
Scatter cheese slices in an even layer on the flattened meat, not overlapping.
Roll the flattened meat from short end to short end into a log. This should be done tightly so as not to lose the cheese. This is best done by lifting the baking paper. Once rolled, seal the ends and seam.
Place in the loaf pan and bake for 1 hour.
While the meatloaf is baking, make your sauce by combining the remaining cherries, honey, and cinnamon. After the meatloaf has baked for an hour, pour half your sauce on the loaf and put it back in the oven to bake for 15 more minutes, or until no longer pink inside.
Slice to serve. You may drizzle the remaining sauce on individual pieces as you serve.